Purpose: To determine whether activity-modifying behaviour mediates the relationship between the severity of knee pain and each of physical function and knee-related quality of life. Methods: A total of 105 participants with medial knee pain and no diagnosis of knee osteoarthritis (mean [SD] age 52.2 [6.7] y) completed two self-report questionnaires. The Questionnaire to Identify Knee Symptoms assessed activity-modifying behaviour; the Knee injury and Osteoarthritis Outcome Score assessed pain severity, physical function, and knee-related quality of life. Simple mediation analysis was performed using linear regression. Results: The unstandardized regression coefficient (±SE) for activity-modifying behaviour revealed partial mediation of the effect of pain severity on physical function (0.31±0.09, p<0.001) and on knee-related quality of life (0.24±0.07, p<0.001). After accounting for activity-modifying behaviour, the variance in physical function that was explained by pain decreased from 45% to 15%, and the variance in knee-related quality of life that was explained by pain decreased from 64% to 25%. Conclusion: Activity-modifying behaviour partially mediates the relationship between pain severity and physical function and between pain severity and knee-related quality of life. Activity-modifying behaviour may thus counteract the impact of knee pain on physical function and knee-related quality of life, which explains why it is used by people with emergent knee pain.
- Content Type Journal Article
- Category Advance Online Article
- Pages 1-8
- DOI 10.3138/ptc.2011-61
- Authors
- Clayon B. Hamilton, Graduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences
- Monica R. Maly, School of Physical Therapy
- Jessica M. Clark, Graduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences
- Mark Speechley, Department of Epidemiology and Biostatistics
- Robert J. Petrella, Department of Family Medicine, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ont.
- Bert M. Chesworth, Graduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences
- Journal Physiotherapy Canada
- Online ISSN 1708-8313
- Print ISSN 0300-0508
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