Calcaneal Quantitative Ultrasound Compared With Hip and Femoral Neck Dual-Energy X-Ray Absorptiometry in People With A Spinal Cord Injury

Publication year: 2012
Source:PM&R, Volume 4, Issue 10

Thomas J. Schnitzer, Nicole Wysocki, Danielle Barkema, James Griffith, Victoria Lent, Meghan Romba, Rachel Welbel, Sheena Bhuva, Bindu Manyam, Sarah Linn

Objective To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting Inpatients and outpatients at a single acute rehabilitation hospital. Participants A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.

Source: http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=IRSSSEARCH&_method=citationSearch&_piikey=S1934148212002821&_version=1&md5=23b0477c0bfe6ebc87ac388f4bb98dcb

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